We recently interviewed Dr. Jagdish Khubchandani, MBBS, Ph.D., a professor of public health at New Mexico State University, on the topic of dementia. Dementia is a general term for cognitive decline and deterioration in mental abilities, affecting over 55 million people worldwide. Although it primarily affects those over the age of 65, it can also occur in younger individuals. While there is no known cure for dementia, some studies suggest that certain vitamins may help delay its onset and progression. In this article, Dr. Khubchandani shares five vitamins that may help reduce the risk of dementia.
1) Vitamin D
Dr. Khubchandani notes, "Vitamin D is a subject of much debate for its potential benefits in preventing or reducing the risk of dementia. There is growing evidence that the vitamin, its receptors, and enzymes can be found throughout the brain and can help remove plaques that cause toxicity leading to dementia. Additionally, Vitamin D helps maintain brain blood vessel function and can reduce the risk of stroke, which is also linked to dementia. However, there is a challenge with reverse causation, which raises the question of whether a lower consumption of vitamin D is due to an unhealthy diet caused by aging and dementia or vice versa."
2) Vitamin E
Dr. Khubchandani explains, "Vitamin E has been extensively researched for its function and effect on many body organs. Studies have shown that its antioxidant properties may help reduce toxic oxidative stress and related cell damage in organs like the brain. However, recent evidence suggests that Vitamin E may also aid in gene expression, electric signal transmission, and neuroprotection. Despite this, the effects of Vitamin E on dementia remain inconclusive due to reverse causation and lack of robust studies."
3) Folic Acid/ Vitamin B
Dr. Khubchandani explains, "Research has shown that folic acid alone may have neuroprotective effects, while other studies suggest that a combination of folic acid and other types of Vitamin B may help prevent cognitive decline and reduce the risk of dementia. Essentially, different types of B vitamins work together to lower the levels of toxic biochemical markers such as homocysteine in the blood, which can otherwise promote clot formation, disrupt blood vessel function, and cause tissue toxicity. By reducing these effects, the brain is able to function properly without any obstruction in blood flow or tissue damage."
4) Vitamin C
Dr. Khubchandani explains, "Vitamin C has a significant role in the development, maturation, and differentiation of nerve cells or neurons, as well as in the formation of the covering of nerve cells. It also aids in the functioning of various neurotransmitters, and its antioxidant properties have been established. Based on these characteristics, it is hypothesized that Vitamin C has a neuroprotective effect on the brain, promoting proper function and reducing toxic stress that is linked with dementia."
5) Multiple Vitamins
Dr. Khubchandani emphasizes the importance of consuming a variety of vitamins for maintaining brain function. He notes that different types and subtypes of vitamins interact with the body organs, including the brain, in various ways. To improve and maintain brain function, it is crucial to consume multiple types of vitamins in optimal amounts. The best way to do this is through natural sources like a healthy diet rich in fruits and vegetables. Additionally, consuming various vitamins can address other body functions that indirectly improve brain function or structure.